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Pier Paolo Olimpieri

 

Personal Informations
Name -- Pier Paolo Olimpieri
Address Via Rocca Priora 44, 00179, Rome, Italy
Telephone +393807533676
E-mail pierpaolo(dot)olimpieri(at)gmail(dot)com
Nationality Italian
Date of birth 8, January, 1984

 

CURRENT POSITION
Dates(from) -- January 2015 - Present
Position Postdoctoral fellowship
Institution Department of Physics ", University of Rome "La Sapienza", P.le Aldo Moro, 5 -- 00185 Rome –Italy.
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EDUCATIONAL BACKGROUND
   
Dates(from) -- October 2011 - January 2015
Title of qualification awarded Ph.D in Pasteurian Sciences
Institution Sapienza University of Rome
Dissertation Molecular interactions: the antibody case
Supervisor Prof. Anna Tramontano,  Department of Physics, Sapienza University of Rome; 
Main activities Analysis of the antigen recognition using computational methods and tools; Prediction of the antibody-antigen interactions using machine learning algorithms; Development of an automatic procedure for antibody humanization
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Dates (from-to) September 2003 - July 2009.
Title of qualification awarded Degree in Pharmaceuticals Chemistry and Technology; grade: 110/110 cum laude.
Institution Sapienza University of Rome
Dissertation "Study on Piperazinyl Carbamates and Ureas as fatty acids amide hydrolase and Transient Receptor Potential Vanilloid 1 dual inhibitors".
Supervisor Prof. Giorgio Ortar,  Department of Pharmaceutical Chemistry, University of Rome “Sapienza”, Rome; 
Main activities From September 2007 to March 2009, researcher in the laboratory of Prof. Giorgio Ortar in Department of Pharmaceutical Chemistry, University of Rome “Sapienza”.
Main topics: Synthesis of TRPV1 and FAAH dual inhibitors, synthesis of TRPA1 antagonists. 
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Institution Catholic University of Sacred Heart
Title of qualification awarded
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 II level specializating Master on Preclinical and Clinical Drug Development.
WORK EXPERIENCES
Dates(from-to) March, 2009 – October, 2010
Name and address of employer ACRAF spa, Angelini Research Center, Piazzale della Stazione, Santa Palombra-Pomezia 00040, Rome, Italy.
Type of business or sector Pharmaceutical Company.
Occupation or position held Internship 
Main activities and responsibilities  Synthesis and Optimization of protein Kinase GSK3 inhibitors.

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Dates(from-to) October 2010 - March 2011
Name and address of employer

ACRAF spa, Angelini Research Center, Piazzale della Stazione, Santa Palombra-Pomezia 00040, Rome, Italy.

Type of business or sector Pharmaceutical Company
Occupation or position held Internship
Main activities and responsibilities  Scaffold optimization of potential analgesic and anti-inflammatory compounds.
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Publications 

  • Olimpieri P.P., Chailyan, A., Tramontano, A. and Marcatili, P. Prediction of site-specific interactions in antibody-antigen complexes: the proABC method and server. Bioinformatics, 29, 2285-2291, doi:10.193/bioinformatics/btt369 (2013)
  • Marcatili P, Olimpieri PP, Chailyan A, Tramontano A. Antibody structural modeling with PIGS. Nature Protocols.9, 2771-2783, doi:10.1038/nprot.2014.189 (2014)
  • Olimpieri PP, Marcatili P, Tramontano A. Tabhu: tools for antibody humanization. Bioinformatics 31(3):434-5. doi: 10.1093/bioinformatics/btu667. (2015)

Conferences and collaborations

  • A computational approach to antibody humanization. BITS annual meeting 2014, Febbraio 26-28 Roma. Oral presentation.
  • A computational approach to antibody humanization. BEMM symposium 2015, Gennaio 23, Roma.
Last Updated ( Thursday, 16 April 2015 14:20 )